Fiona Doetsch
University of Basel, Switzerland
- Position : Head of research group
- Website : Research Group Fiona Doetsch
Fiona Doetsch obtained her B.Sc. at McGill University in Montreal, Canada and her Ph.D. at Rockefeller University in New York City, USA. She was a Junior Fellow of the Society of Fellows at Harvard University and a Fellow at the Radcliffe Institute for Advanced Studies before joining Columbia University as faculty in 2003. In 2014, she moved to the Biozentrum, University of Basel in Switzerland where she is Professor of Molecular Stem Cell Biology. She is a member of EMBO, and has received numerous awards including the David and Lucile Packard Fellowship for Science and Engineering, the Irma T. Hirschl Scholar Award, the Harold and Golden Lamport Award for Excellence in Basic Science Research and an ERC Advanced Grant.
Title of talk : Stem cells in the adult brain: Regulation and diversity
Abstract
Neural stem cells reside in specialized niches in the adult mammalian brain. Adult neural stem cells dynamically integrate intrinsic and extrinsic signals to either maintain the quiescent state or to become activated to divide and generate neurons and glia. I will present our recent findings highlighting adult neural stem cell heterogeneity, including the identification of novel gliogenic domains and cell types, and the key roles of physiological states and long-range signals in the regulation of regionally distinct pools of adult neural stem cells.